Development of Matrix Metalloproteinase-2 Inhibitors for Cardioprotection

نویسندگان

  • Péter Bencsik
  • Krisztina Kupai
  • Anikó Görbe
  • Éva Kenyeres
  • Zoltán V. Varga
  • János Pálóczi
  • Renáta Gáspár
  • László Kovács
  • Lutz Weber
  • Ferenc Takács
  • István Hajdú
  • Gabriella Fabó
  • Sándor Cseh
  • László Barna
  • Tamás Csont
  • Csaba Csonka
  • György Dormán
  • Péter Ferdinandy
چکیده

Citation: Bencsik P, Kupai K, Görbe A, Kenyeres É, Varga ZV, Pálóczi J, Gáspár R, Kovács L, Weber L, Takács F, Hajdú I, Fabó G, Cseh S, Barna L, Csont T, Csonka C, Dormán G and Ferdinandy P (2018) Development of Matrix Metalloproteinase-2 Inhibitors for Cardioprotection. Front. Pharmacol. 9:296. doi: 10.3389/fphar.2018.00296 Development of Matrix Metalloproteinase-2 Inhibitors for Cardioprotection

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Two Matrix Metalloproteinase Inhibitors from Scrophularia Striata Boiss

Many species belonging to the Scrophularia genus have been used since ancient times as folk remedies for many medical conditions such as scrofulas, scabies, tumors, eczema, psoriasis, inflammations. The aim of this study was to characterize the matrix metalloproteinases (MMPs) inhibitor compounds of the Scrophularia striata extract by bio-guide fractionation. The aerial parts of S. striata were...

متن کامل

Two Matrix Metalloproteinase Inhibitors from Scrophularia Striata Boiss

Many species belonging to the Scrophularia genus have been used since ancient times as folk remedies for many medical conditions such as scrofulas, scabies, tumors, eczema, psoriasis, inflammations. The aim of this study was to characterize the matrix metalloproteinases (MMPs) inhibitor compounds of the Scrophularia striata extract by bio-guide fractionation. The aerial parts of S. striata were...

متن کامل

Impact of the Synchronization of portulaca oleracea and Aerobic Training on Levels of MMP2 and MMP9 and TIMP1 in Diabetic Women Type II

Background: Diabetes has the most important role in development of tissue damage, and by affecting intercellular matrices, may lead to structural and functional changes that ultimately cause failure of related tissue or organ. Exercise and herbal medicine can be effective in reducing organ failure. This study aims to assess the effect of aerobic training combined with consumption of portulaca o...

متن کامل

Expression of Matrix Metalloproteinase-2/9 and Tissue Inhibitor of Metalloproteinase-1/2 as Predictive Factors in Oropharyngeal Squamous Cell Carcinoma

Introduction: Metalloproteinases and their tissue inhibitors play an important role in the metastases formation. A multistage process of carcinogenesis requires the involvement of numerous enzymes and compounds that facilitate the expansion of tumor cells. The formation of metastases depends on both metalloproteinases and tissue inhibitors activation leading to the acti...

متن کامل

P 88: Matrix Metalloproteinases in Neuroinflammation

Matrix metalloproteinases (MMPs) are a family of neutral proteinases that are important in normal development, cellular differentiation or migration, angiogenesis, neurogenesis, wound repair, and a wide range of pathological processes such as oxidative stress and neuroinflammation. MMPs have been demonstrated to increase the permeability of the blood–brain barrier (BBB) by degrading the c...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:

دوره   شماره 

صفحات  -

تاریخ انتشار 2018